Investigation of the concentration of chemical compounds in toys

Document Type : Original Article

Author
Student Research Committee, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran
Abstract
This study was conducted to investigate the concentration of hazardous chemical compounds in children's toys available in Iran, addressing a significant data gap in regional market surveillance and the associated health risks for a vulnerable population. Using a stratified random sampling approach, 120 toys categorized as plastic, painted wood, rubber, and plush were collected from retail and online sources. Samples were analyzed via inductively coupled plasma mass spectrometry (ICP-MS) for heavy metals and gas chromatography–mass spectrometry (GC-MS) for organic compounds, including phthalates and flame retardants. The results identified clear material-specific contamination patterns. Rubber toys presented the highest concentrations of phthalates, with di(2-ethylhexyl) phthalate (DEHP) exceeding the European Union safety limit in 66.7% of samples. Painted wood toys showed elevated levels of lead and chromium, exceeding limits in 23.3% and 30.0% of samples, respectively. In contrast, plush toys demonstrated negligible chemical burdens. Statistical analysis confirmed significant differences between material categories, and a quantitative risk assessment indicated a potential health hazard (Hazard Quotient > 1) from exposure to lead in painted wood and DEHP in rubber toys. The conclusion underscores an urgent need for enhanced regulatory enforcement, focusing on high-risk material categories, alongside policies promoting supply chain transparency and the adoption of safer alternative materials in toy manufacturing to protect children's health.

Graphical Abstract

Investigation of the concentration of chemical compounds in toys

Highlights

·       Rubber toys show the highest phthalate levels

·       Painted wood toys contain elevated lead, chromium

·       Plush toys safest; comply with all limits

·       Regulatory gaps found in high-risk categories

·       Material type dictates chemical exposure risk

Keywords
Subjects

Al-Natsheh, M., Alawi, M., Fayyad, M., & Tarawneh, I. (2015). Simultaneous GC–MS determination of eight phthalates in total and migrated portions of plasticized polymeric toys and childcare articles. Journal of Chromatography B, 985, 103-109. DOI:  10.1016/j.jchromb.2015.01.010
Al-Qutob, M., Asafra, A., Nashashibi, T., & Qutob, A. A. (2014). Determination of different trace heavy metals in children’s plastic toys imported to the West Bank/Palestine by ICP/MS-environmental and health aspects. Journal of Environmental Protection, 5(12), 1104-1110. http://dx.doi.org/10.4236/jep.2014.512108
Al Kindi, G., & Ali, Z. (2020). Lead, Nickel and Cadmium in the coating of children’s toys effects and influencing factors. IOP conference series: materials science and engineering. DOI:10.1088/1757-899X/737/1/012186.
Alsaigh, R. A., Althobaiti, H. S., Ahmad, N., & Khan, M. R. (2024). Presence of hazardous chemical elements in low-cost children's toys: A risk to their development in early childhood. Journal of King Saud University-Science, 36(6), 103206. https://doi.org/10.1016/j.jksus.2024.103206.
Aurisano, N., Fantke, P., Huang, L., & Jolliet, O. (2022). Estimating mouthing exposure to chemicals in children’s products. Journal of exposure Science & Environmental Epidemiology, 32(1), 94-102. DOI:  10.1038/s41370-021-00354-0
Aurisano, N., Huang, L., Canals, L. M., Jolliet, O., & Fantke, P. (2021). Chemicals of concern in plastic toys. Environment international, 146, 106194. DOI: 10.1016/j.envint.2020.106194
Aurisano, N., Huang, L., Milà i Canals, L., Jolliet, O., & Fantke, P. (2021, 2021/01/01/). Chemicals of concern in plastic toys. Environment International, 146, 106194. https://doi.org/https://doi.org/10.1016/j.envint.2020.106194
Becker, M., Edwards, S., & Massey, R. I. (2010). Toxic chemicals in toys and children’s products: limitations of current responses and recommendations for government and industry. Environmental Science & Technology, 44(21), 7986-7991. DOI: 10.1021/es1009407
Bekki, K., Eguchi, A., Takaguchi, K., Inaba, Y., Yukawa, K., Yoshida, S., & Azuma, K. (2024). Comprehensive survey on the use of plastic additives in toy products used in Japan. Environmental Health and Preventive Medicine, 29, 43-43. https://doi.org/10.1265/ehpm.24-00054
Börjeson, N., & Ågerstrand, M. (2025). The problems that we have today, are yesterday’s solutions”: enabling circular non-toxic supply chains. Circular Economy and Sustainability, 5(3), 2273-2293. https://doi.org/10.1007/s43615-025-00501-x
Burgos, H. D., Souza-Araujoa, J., Benavides, L., Macedo, J., Cardoso, R., Mancini, S., Harrad, S., & Rosa, A. H. (2024). Concentrations and legislative aspects of brominated flame retardants in plastic waste electrical and electronic equipment in Brazil. Science of the Total Environment, 906, 167349. https://doi.org/10.1016/j.scitotenv.2023.167349
Christova-Bagdassarian, V., Tishkova, J., & Tachev, A. (2017). Determination of dibutyl phthalate (DBP), benzyl butyl phthalate (BBP) and bis (2-Ethylhexyl) phthalate (DEHP) in soft plastic toys and the first survey of the bulgarian market. Food and Environment Safety Journal, 16(4).
Häkkinen, P. Control of chemicals in articles. (2010). avialable at:  http://hdl.handle.net/10138/37989
Halpaap, A., & Dittkrist, J. (2018). Sustainable chemistry in the global chemicals and waste management agenda. Current Opinion in Green and Sustainable Chemistry, 9, 25-29. https://doi.org/10.1016/j.cogsc.2017.11.001
Halsband, C., Sørensen, L., Booth, A. M., & Herzke, D. (2020). Car tire crumb rubber: does leaching produce a toxic chemical cocktail in coastal marine systems? Frontiers in Environmental Science, 8, 125. https://doi.org/10.3389/fenvs.2020.00125
Ivanovic, N., Milenkovic, M., Protic, A., Jovanovic, V., Djordjevic, B., & Dodevska, M. (2024). Phthalate content in toy samples available on the market of the Republic of Serbia. Analytical Methods, 16(34), 5835-5844. https://doi.org/10.1039/D4AY01092B
Karaś, K., & Frankowski, M. (2018, Nov 19). Analysis of Hazardous Elements in Children Toys: Multi-Elemental Determination by Chromatography and Spectrometry Methods. Molecules, 23(11). https://doi.org/10.3390/molecules23113017
Karaś, K., & Frankowski, M. (2018). Analysis of Hazardous Elements in Children Toys: Multi-Elemental Determination by Chromatography and Spectrometry Methods. Molecules, 23(11), 3017. https://www.mdpi.com/1420-3049/23/11/3017
Landrigan, P. J., & Miodovnik, A. (2011). Children's health and the environment: an overview. Mount Sinai Journal of Medicine: A Journal of Translational and Personalized Medicine, 78(1), 1-10. https://doi.org/10.1002/msj.20236
Lin, J., Chen, W., Zhu, H., & Wang, C. (2015, 10/11). Determination of free and total phthalates in commercial whole milk products in different packaging materials by gas chromatography-mass spectrometry. Journal of Dairy Science, 98. https://doi.org/10.3168/jds.2015-10066
Lulei, M. (2008). REACH: the guidance documents of the European Chemicals Agency (ECHA). Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz, 51(12), 1444-1452.
Mazur, L. J. (2003). Pediatric environmental health. Current Problems in Pediatric and Adolescent Health Care, 33(1), 6-25. https://doi.org/https://doi.org/10.1067/mps.2003.1
Mbughuni, M. M., Jannetto, P. J., & Langman, L. J. (2016, Dec). Mass Spectrometry Applications for Toxicology. Ejifcc, 27(4), 272-287. PMCID: PMC5282913
Olisah, C., Melymuk, L., Audy, O., Kukucka, P., Pribylova, P., & Boudot, M. (2024). Extremely high levels of PBDEs in children’s toys from European markets: causes and implications for the circular economy. Environmental Sciences Europe, 36(1), 183. https://doi.org/10.1186/s12302-024-00999-2
Omolaoye, J., Uzairu, A., & Gimba, C. (2010). Heavy metal assessment of some soft plastic toys imported into Nigeria from China. Journal of Environmental Chemistry and Ecotoxicology, 2(8), 126-130.
Pan, S., Qiu, Y., Li, M., Yang, Z., & Liang, D. (2022, 2022/05/01). Recent Developments in the Determination of PM2.5 Chemical Composition. Bulletin of Environmental Contamination and Toxicology, 108(5), 819-823. https://doi.org/10.1007/s00128-022-03510-w
Sindiku, O., & Osibanjo, O. (2011). Some priority heavy metals in children toy's imported to Nigeria. Journal of Toxicology and Environmental Health Sciences, 3(4), 109-115.
Szollosi-Mota, A., Suvar, N. S., Prodan, M., Nalboc, V. I., & Toplician, A. I. (2025). Determination of different heavy metals content in children toys using ICP-OES analysis method. International Multidisciplinary Scientific GeoConference: SGEM, 5(1), 69-76. DOI: 10.5593/sgem2025/5.1/s19.008
Tachev, A., & Christova-Bagdassarian, V. (2015). Phthalate Plasticizers and safety of toys - problems and perspectives. Emergent Life Science Research, 1(1), 4-7.
Thierse, H.-J., & Luch, A. (2019). Consumer protection and risk assessment: sensitising substances in consumer products. Allergo Journal International, 28(6), 167-182. https://doi.org/10.1007/s40629-019-0093-3
Vuong, A. M., Yolton, K., Dietrich, K. N., Braun, J. M., Lanphear, B. P., & Chen, A. (2018). Exposure to polybrominated diphenyl ethers (PBDEs) and child behavior: Current findings and future directions. Hormones and Behavior, 101, 94-104. https://doi.org/https://doi.org/10.1016/j.yhbeh.2017.11.008
Volume 1, Issue 1
Winter 2026
Pages 43-48

  • Receive Date 20 October 2025
  • Revise Date 01 January 2026
  • Accept Date 01 January 2026
  • First Publish Date 01 January 2026
  • Publish Date 01 January 2026